Opioid Detox in Los Angeles

Medically reviewed by Dr. Eric Chegouri, MD, Medical Director · Last reviewed November 7, 2026

Coming off prescription opioids is rarely as simple as "just stopping." Whether you have been taking oxycodone after a surgery, hydrocodone for a back injury, or more pills than you were prescribed for longer than you planned, your body has adapted, and stopping suddenly can bring days of misery and a high risk of going back. Medical detox gives you a safer, steadier way through.

Reggie's provides inpatient opioid detox at our private hilltop campus in Sun Valley, in the northeast San Fernando Valley, for people across Los Angeles and Southern California. This page explains who prescription opioid detox is for, what happens from the first call through the first few days, how medication and comfort care work, and what comes next.

Who needs prescription opioid detox?

Many people who come to us never bought a drug on the street. They started with a legitimate prescription and found, months or years later, that they could not stop without getting sick. Detox may be the right next step if any of these sound familiar:

• You feel unwell, anxious or achy when a dose is late, and better soon after taking one.
• You take more than prescribed, run out early, or use pills from friends, family or online.
• You have tried to taper with your doctor and could not stick to it.
• You are combining opioids with alcohol, benzodiazepines or sleep medication.
• You have a medical or mental-health condition that makes withdrawal riskier.
• You are worried a pill you took may not have been what it seemed.

If you were prescribed opioids, take them as directed and simply want to come off, a gradual taper with your prescriber is often the first option. Inpatient detox becomes the better choice when tapering has not worked, when use has moved beyond the prescription, or when other substances or health issues are involved. Our signs of opioid addiction guide can help you sort out where you stand.

What does opioid detox at Reggie's include?

Detox at Reggie's is medically supervised from start to finish and built around safety, comfort and continuity.

• Initial assessment: bloodwork, vital signs, a medical history and a mental-health screening.
• 24/7 nursing with an on-call physician, under the oversight of our Medical Director.
• Comfort medications and tapering protocols selected for your situation.
• Medication-assisted treatment with buprenorphine (Suboxone) for many clients, and planning for naltrexone where it fits.
• A private suite with a spa-style bathroom and mountain views over the San Fernando Valley.
• Chef-prepared meals to rebuild nutrition and energy.
• Light counseling once you are stable, and family updates with your consent.
• A direct transition to residential treatment on the same campus.

Detox also treats other substances that often travel with opioids, including benzodiazepines and alcohol, whose withdrawal can be dangerous. Learn more about our full inpatient detox program.

How do you get admitted to opioid detox?

Admission is designed to be fast, because the moment someone is ready can pass quickly.

1. Step 1Call admissions

   Call (818) 355-1200, any time of day or night. A team member asks about your opioid use, other substances, health and goals. You can call for yourself or a loved one.

2. Step 2Verify insurance

   With your permission, we check your benefits for free, usually in 15 to 30 minutes, and explain what we find.

3. Step 3Begin treatment

   Most people complete the process in under two hours and are admitted the same day. Transportation can be coordinated if needed.

We welcome people from every corner of Los Angeles, from Burbank and Pasadena to the Westside and the Antelope Valley. See all the communities we serve.

What happens in the first 72 hours?

The first three days are usually the hardest part of opioid withdrawal, and also where medical care makes the biggest difference.

1. ArrivalSettle and assess

   Vitals, bloodwork and a mental-health screening. The care team learns when you last took an opioid, which kind, and how much, then builds your plan.

2. Hours 6–24Early withdrawal

   For short-acting pills, early symptoms appear. Nurses monitor symptoms closely and begin comfort care. For extended-release pills, this stage may come later.

3. Hours 24–48Medication decisions

   When withdrawal has developed enough, the physician may begin buprenorphine. For many people, a well-timed start brings noticeable relief.

4. Hours 48–72Through the peak

   Symptoms typically crest. Fluids, rest, nutrition and adjustments to medication keep you as comfortable and safe as possible.

Every clock is different. Your team will explain each step and adjust the plan as your body responds. For a detailed look at symptoms and phases, read our opioid withdrawal timeline.

How is withdrawal kept comfortable?

Good detox treats the whole experience, not just the numbers on a chart. Depending on your needs, your physician may use medications for nausea, diarrhea, muscle aches, anxiety, restlessness and sleep. Nurses watch for dehydration and help you stay ahead of it.

Comfort also comes from the environment. A quiet private room, a warm shower, real food and a view of the San Gabriel Mountains are not luxuries for their own sake. They help people sleep, eat and stay through the hard days rather than leave early.

Will I get Suboxone or naltrexone in detox?

Medication-assisted treatment is one of the most effective tools for opioid use disorder, and it often begins in detox.

Which path fits, and for how long, is a decision you make with your physician. Reggie's does not offer methadone, which in the U.S. is dispensed only through federally certified opioid treatment programs; if you are already on methadone, tell us when you call so we can talk through options. Our MAT program page explains each medication in depth.

What if I still need pain treatment?

For many people coming off prescription opioids, pain is the reason they started. Detox does not ask you to pretend it is not there. Expect your care team to ask about your pain history, use non-opioid approaches during detox, and help you plan for pain care afterward. Withdrawal often makes pain feel worse for a while before it improves.

After detox, it helps to tell every doctor, dentist and surgeon that you are in recovery, and to coordinate in advance if a procedure is planned. Movement, physical therapy, sleep and treatment of depression or anxiety can all change how pain feels. If you are on buprenorphine, keep every prescriber informed.

How long does opioid detox take?

Inpatient detox at Reggie's typically lasts 5 to 10 days. People withdrawing from short-acting pills are often at the shorter end; extended-release opioids, heavier use, other substances or medical complications can lengthen the stay. The decision is clinical, not a fixed number, and it is made with you.

Some symptoms, such as poor sleep, low energy and cravings, can continue beyond detox. That is expected, and it is why ongoing treatment matters.

Does insurance cover opioid detox?

Many PPO plans include benefits for medically necessary detox and medication-assisted treatment, though what is covered depends on your plan. Reggie's works with most major PPO plans. Our free verification usually takes 15 to 30 minutes, and your employer is not notified. HMO options for our level of care are more limited, but we will point you toward resources, and self-pay and financing options can be discussed. We generally don't accept Medi-Cal, but if that's your coverage we'll connect you with a provider who does.

Start with our insurance verification page, or use the Insurance Decoder to understand your benefits before you call.

What happens after opioid detox?

Detox ends physical withdrawal. It does not treat the patterns, pain, stress and cravings that keep opioid use going, and stopping at detox leaves you with lower tolerance and high overdose risk. Most people continue straight into care:

Medication, therapy such as CBT and relapse prevention, and dual-diagnosis care for depression, anxiety or trauma carry through each stage. Treatment is confidential under HIPAA and 42 CFR Part 2, and we can help with FMLA paperwork if you need time away from work.